Antibody-Drug Conjugates are highly potent biopharmaceutical drugs built by attaching a small cytotoxic molecule or another therapeutic agent to an antibody. Using the antibody’s property to target a specific antigen only found on target cells, ADCs deliver the highly potent drugs with a very high specificity to target cells whilst sparing healthy cells. In this way ADCs maximize the efficacy and minimize systemic exposure with associated side effects. ADCs combine the two major advantages of chemotherapy and treatment with biologicals: they are cost-effective and at the same time highly specific with high efficacy and minor systemic effects. Genagon is exploring several ADC assets including the lead drug candidate, GEN201.